on 1 , 3 , 4 - Thiadiazole derivaties and it ’ s Pharmacological activities .

Abstract: Heterocyclic compounds occupy a central position among those molecule that makes life possible. The chemistry of heterocyclic compounds has been an interesting field of study for a long time. Heterocyclic nucleus 1,3,4thiadiazole constitutes constitutes an important class of compounds for new drug development. The synthesis of novel thiadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades. During the recent years there has been intense investigation of different classes of thiadiazole compounds, many of which possess extensive pharmacological activeties. Among of these compounds having 1,3,4,_thiadiazole nucleus are known to exhibit unique anti-inflammatory, analgesic, antimicrobial, antitumor, antifungal, antimycobacterial , anticonvulsant, antI-diabetic, antiviral, activities. So far, modification of the thiadiazole ring have proven highly effective with improved potency and lesser toxicity. The present review highlights the recently synthesized thiadiazole possessing important biological activities.